Christy K. Holland, Ph.D. - Curriculum Vitae

Director of Ultrasound Image Guided Therapeutics Lab

Department of Internal Medicine

Division of Cardiovascular Diseases

Email: christy.holland@uc.edu



EDUCATION AND PROFESSIONAL APPOINTMENTS

Christy K. Holland attended Wellesley College where she majored in Physics and Music.  Thereafter she completed an M.S., M.Phil. and Ph.D. at Yale University in Engineering and Applied Science.  Dr. Holland is a Professor in the Department of Internal Medicine, Division of Cardiovascular Diseases, College of Medicine and Biomedical Engineering Program (BME) in the College of Engineering and Applied Science at the University of Cincinnati.  She is a fellow of both the Acoustical Society of America (ASA) and the American Institute of Ultrasound in Medicine (AIUM).  She assumed the editorship of Ultrasound in Medicine and Biology the official Journal of the World Federation of Ultrasound in Medicine and Biology, in July 2006.  Dr. Holland is actively involved in teaching biomedical engineering and medical imaging in the BME undergraduate and graduate curriculum and served 2008 to 2009 as the Director of Graduate Studies.  She mentors and advises students within and outside of BME educational programs.  Christy Holland's research interests include ultrasound-enhanced thrombolysis for stroke therapy, ultrasound-mediated drug delivery, bioeffects of diagnostic and therapeutic ultrasound, and acoustic cavitation. As a result of her research, Dr. Holland has gained wide recognition at UC, nationally and internationally for her excellence and contributions in ultrasound research.  Dr. Holland has consulted professionally in the fields of medical ultrasound and architectural acoustics and continues to perform locally with the Knox Choir under the direction of Earl Rivers.  



RESEARCH INTERESTS

Christy Holland's research interests include ultrasound-assisted thrombolysis for stroke therapy, ultrasound-mediated drug delivery, bioeffects of diagnostic and therapeutic ultrasound, and acoustic cavitation. She is the principal investigator of an NIH RO1 grant entitled, “Ultrasound-Assisted Thrombolysis for Stroke Therapy.” Successful completion of these studies will contribute significantly to her long-term goal to develop an ultrasound-assisted thrombolysis system that delivers and enhances thrombolytic therapy in the cerebral vasculature and rapidly restores perfusion after ischemic stroke. Dr. Holland is also principal investigator of two subcontracts to NIH RO1 grants entitled, “Targeted Liposomes for Acoustic Cardiovascular Imaging” and “Echogenic Targeted Liposomes for Transfection/Drug Delivery” in collaboration with investigators at the University of Texas Health Science Center in Houston, Texas. The goal of these projects is to develop echogenic liposomes to highlight and enhance vascular pathology, to determine, quantitate, and characterize the stage, extent, and pathophysiologic development of atherosclerosis. This research will aid in directing therapy to improve physiologic flow following clinical intervention. As a result of her research, Dr. Holland has gained wide recognition at UC, nationally and internationally for her excellence and contributions in ultrasound research.

PUBLICATIONS: SCOPUS  PUBMED


CONTACT

Image-Guided Ultrasound Therapeutics Laboratory
University of Cincinnati
231 Albert Sabin Way, CVC, 3935
Cincinnati, Ohio, 45267-0586
Phone: (513) 558-5675
Email: christy.holland@uc.edu